_:vb50946476 . _:vb50946476 . _:vb50946476 "An endocrine system disease characterized by early activation of the hypothalamic-pituitary-gonadal axis resulting in development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys."^^ . _:vb50946476 . _:vb50946476 . _:vb50946476 . _:vb50946476 "url:https://pubmed.ncbi.nlm.nih.gov/30086862/"^^ . _:vb50946476 "url:https://pubmed.ncbi.nlm.nih.gov/23738509/"^^ .