_:vb50945873 . _:vb50945873 "A primary immunodeficiency disease characterized by increased susceptibility to mycobacterial infection after BCG vaccination and impaired cellular responses to IL-12, IFN-alpha/beta, IL-23, and IL-10 that has_material_basis_in homozygous or compound heterozygous mutation in TYK2 on chromosome 19p13.2."^^ . _:vb50945873 . _:vb50945873 . _:vb50945873 . _:vb50945873 "url:https://pubmed.ncbi.nlm.nih.gov/26304966/"^^ . _:vb50945873 .