_:vb50941013 . _:vb50941013 . _:vb50941013 . _:vb50941013 "url:https://www.ncbi.nlm.nih.gov/pubmed/21848462"^^ . _:vb50941013 . _:vb50941013 . _:vb50941013 "A psoriasis characterized by sudden, repeated episodes of high-grade fever, generalized rash, and disseminated pustules, with hyperleukocytosis and elevated serum levels of C-reactive protein that has_material_basis_in homozygous or compound heterozygous mutation in the IL36RN gene on chromosome 2q14."^^ .