_:vb50938551 . _:vb50938551 "A pigmentation disease characterized by lesions that initially arise as letiginous, hyperpigmented macules in a reticular pattern on the dorsal aspect of the hands and feet. Over time, lesions may spread proximally and may darken; palmoplantar pitting and dermatoglyphic disruption may also be present."^^ . _:vb50938551 . _:vb50938551 . _:vb50938551 "url:https://www.ncbi.nlm.nih.gov/pubmed/22808308"^^ . _:vb50938551 . _:vb50938551 .