_:vb50936847 . _:vb50936847 . _:vb50936847 . _:vb50936847 "A rickets has_material_basis in X-linked mutations in the PHEX gene that lead to increased circulating levels of FGF-23, a phosphate-regulating hormone (phosphatonin), that leads to reduced renal phosphate reabsorption and consequently abnormal bone mineralization."^^ . _:vb50936847 "url:https://rarediseases.info.nih.gov/diseases/12943/x-linked-hypophosphatemia"^^ . _:vb50936847 . _:vb50936847 "url:http://en.wikipedia.org/wiki/X-linked_hypophosphatemia"^^ . _:vb50936847 . _:vb50936847 .