. _:vb50945882 . "IMD45"^^ . _:vb50945882 . . _:vb50945882 . "DOID:0111994"^^ . . "A primary immunodeficiency disease characterized by impaired control the replication of certain viruses and failure to develop an antiviral state in response to alpha-interferon or beta-interferon that has_material_basis_in homozygous or compound heterozygous mutation in IFNAR2 on chromosome 21q22.11."^^ . "immunodeficiency 45"^^ . . _:vb50945882 . "disease_ontology"^^ . _:vb50945882 . "OMIM:616669"^^ .