"mal de Meleda"@en . . "transgrediens palmoplantar keratoderma of Siemens"@en . "ORDO:87503"^^ . "ICD10CM:Q82.8"^^ . "A palmoplantar keratosis characterized by autosomal recessive inheritance of symmetric palmoplantar hyperkeratosis that progressively extends to the dorsal surfaces of hands and feet and ichthyotic changes elsewhere that has material_basis_in homozygous mutation in the SLURP1 gene on chromosome 8q24."^^ . . "disease_ontology"^^ . . "DOID:0060862"^^ . "OMIM:248300"^^ . "Meleda disease"@en . "keratosis palmoplantaris transgrediens of Siemens"@en .