"OMIM mapping confirmed by DO. [SN]."^^ . _:vb50938075 . . . . _:vb50938076 . _:vb50938075 . _:vb50938075 . "DNA ligase IV deficiency"^^ . _:vb50938075 . "LIG4 Syndrome"@en . _:vb50938076 . . "A combined T cell and B cell immunodeficiency that has_material_basis_in a mutation in the LIG4 gene, a DNA ligase, encoding a protein essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). Patients present with immunodeficiency and developmental and growth delay."^^ . _:vb50938075 . "DOID:0060021"^^ . "OMIM:606593"^^ . "disease_ontology"^^ . _:vb50938076 . _:vb50938076 . _:vb50938076 .